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65 lines
1.5 KiB
65 lines
1.5 KiB
2 years ago
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COMMENT
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Iclamp2.mod: Electrode current injection, revised for our own use
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I specifically needed more step changes in a single waveform than
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were provided by the default code. This routine gives us 5 levels:
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holding, 3 steps, and a final (holding?) level.
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This version generates a pulse of duration at amplitude I for
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onset times in the vector onset[STEP] and durations in dur[STEP]
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Each pulse is independent and pulses _could_ overlap.
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Since this is an electrode current, positive values of I depolarize the cell
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and in the presence of the extracellular mechanism there will be a change
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in vext since I is not a transmembrane current but a current injected
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directly to the inside of the cell.
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(modified and borrowed extensively from other Neuron code,
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2001-2002. Paul B. Manis)
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ENDCOMMENT
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INDEPENDENT {t FROM 0 TO 1 WITH 1 (ms)}
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DEFINE NSTEP 5 : maximum number of steps supported in this mechanism
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NEURON {
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POINT_PROCESS IClamp2
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RANGE onset, dur, amp, i
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ELECTRODE_CURRENT i
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}
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UNITS {
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(nA) = (nanoamp)
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}
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PARAMETER {
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}
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ASSIGNED {
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i (nA)
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index
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onset[NSTEP] (ms)
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dur[NSTEP] (ms)
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amp[NSTEP] (nA)
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pu
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}
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INITIAL {
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i = 0 (nA)
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index = 0
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pu = 0
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}
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:
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: at each onset time, a pulse of duration dur is generated.
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:
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BREAKPOINT {
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i = 0
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FROM index = 0 TO NSTEP-1 {
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if(t > onset[index]) {
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if(t < (dur[index]+onset[index])) {
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i = i + amp[index] : allows overlap
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} : end of if condition
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} :end of second if condition
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} : end of "FROM" (for) loop
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} : end of breakpoint
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