: Ca diffusion in a Purkinje cell : Created 8/15/02 - nwg NEURON { SUFFIX cadiff USEION ca READ ica, cai WRITE cai RANGE ca GLOBAL depth, beta } UNITS { (mV) = (millivolt) (mA) = (milliamp) (mM) = (milli/liter) (um) = (micron) } CONSTANT { F = 9.6485e4 (coul) } PARAMETER { cai (mM) dt (ms) depth = 0.1 (um) beta = 1 (/ms) } ASSIGNED { ica (mA/cm2) } STATE { ca (mM) } INITIAL { ca = 0.0001 } BREAKPOINT { ca = ca + (10000.0) * dt * ( ( -1/(2*F)*ica / (depth)) - (0.0001) * beta * ca ) if ( ca < 1e-4 ) {: minimum 100 nM Ca ca = 1e-4 } cai = ca }