""" Test generating a series of EPSPs in a bushy cell in response to tone pip. This script: 1. Creates one SGC and one bushy cell. 2. Connects the two cells with a synapse. 3. Specifies a tone pip input to the SGC cell. 4. Records the bushy cell Vm. The auditory nerve spike train is generated automatically by the DummySGC class using the tone pip. For lower-level access to the auditory nerve model, see the test_an_model.py and test_sound_stim.py examples. The simulator that is run depends on what is available and how the script is called. python examples/test_sgc_input.py [cochlea | matlab] will try to use the specified simulator. If no simulator is specified, it will try to use cochlea or matlab, in that order. """ import sys import numpy as np import pyqtgraph as pg from neuron import h from cnmodel.protocols import Protocol from cnmodel import cells from cnmodel.util import sound from cnmodel.util import custom_init class SGCInputTest(Protocol): def run(self, temp=34.0, dt=0.025, seed=575982035, simulator=None): preCell = cells.DummySGC(cf=4000, sr=2) postCell = cells.Bushy.create() synapse = preCell.connect(postCell) self.pre_cell = preCell self.post_cell = postCell self.synapse = synapse self.stim = sound.TonePip( rate=100e3, duration=0.1, f0=4000, dbspl=80, ramp_duration=2.5e-3, pip_duration=0.04, pip_start=[0.02], ) preCell.set_sound_stim(self.stim, seed=seed, simulator=simulator) self["vm"] = postCell.soma(0.5)._ref_v # self['prevm'] = preCell.soma(0.5)._ref_v for i in range(30): self["xmtr%d" % i] = synapse.terminal.relsite._ref_XMTR[i] synapse.terminal.relsite.Dep_Flag = False self["t"] = h._ref_t h.tstop = 100.0 # duration of a run h.celsius = temp h.dt = dt custom_init() h.run() def show(self): self.win = pg.GraphicsWindow() p1 = self.win.addPlot(title="Bushy Vm") p1.plot(self["t"], self["vm"]) p2 = self.win.addPlot(title="xmtr", row=1, col=0) for i in range(30): p2.plot(self["t"], self["xmtr%d" % i], pen=(i, 15)) p2.setXLink(p1) p3 = self.win.addPlot(title="AN spikes", row=2, col=0) vt = pg.VTickGroup(self.pre_cell._spiketrain) p3.addItem(vt) p3.setXLink(p1) p4 = self.win.addPlot(title="stim", row=3, col=0) p4.plot(self.stim.time * 1000, self.stim.sound) p4.setXLink(p1) self.win.show() if __name__ == "__main__": simulator = None if len(sys.argv) > 1: simulator = sys.argv[1] prot = SGCInputTest() prot.run(simulator=simulator) prot.show() if sys.flags.interactive == 0: pg.QtGui.QApplication.exec_()