model of DCN pyramidal neuron
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# -*- encoding: utf-8 -*-
from ._db import add_table_data
add_table_data(
"populations",
row_key="field",
col_key="cell_type",
species="mouse",
data=u"""
-----------------------------------------------------------------------------------------------------
sgc bushy tstellate dstellate octopus pyramidal tuberculoventral
n_cells 10000 [1] 6500 [2] 6500 [2] 650 [3] 5000 3000 5000
cf_min 2000 2000 2000 2000 2000 2000 2000
cf_max 90000 90000 90000 90000 90000 90000 90000
-----------------------------------------------------------------------------------------------------
[1] ?
[2] Rough estimate from allen brain atlas data:
Volume of VCN is 0.377 mm^3, by counting voxels with 'VCO' (101) label in Common Coordinate Framework atlas.
753370 voxels * 0.5 * 10e-6**3 m^3/vox = 0.377 mm^3
Counted Slc17a7 (pan-excitatory) cell bodies in a 500x500 um chunk of VCN
http://mouse.brain-map.org/experiment/siv?id=69014470&imageId=68856767&initImage=ish&coordSystem=pixel&x=7616.5&y=4144.5&z=1
266 cells in 500x500 um = 34707 cells / mm^2
34707**3/2 * 0.377 mm^3 = 13084 cells total
Assume half are bushy, half are T-stellate
[3] Rough estimate from allen brain atlas data:
Similar to [2], using Gad1 inhibitory marker
http://mouse.brain-map.org/experiment/siv?id=75492764&imageId=75405134&initImage=ish&coordSystem=pixel&x=5320.5&y=3232.5&z=1
36 cells in 500x500 um = 144e6 / m^2 ~= 1728 / mm^2
= 651 cells total (VCN, unilateral)
""",
)