model of DCN pyramidal neuron
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NEURON {
SUFFIX capump
USEION ca READ cai WRITE ica
RANGE vmax, kmp, ica
}
UNITS {
(uM) = (micro/liter)
(mM) = (milli/liter)
(mA) = (milliamp)
}
PARAMETER {
vmax = .0667 (mA/cm2) <0, 1e6>: at 6.3 deg, Q10 = 3
kmp = .2 (uM) <0, 1e6>
}
ASSIGNED {
celsius (degC)
ica (mA/cm2)
cai (mM)
}
LOCAL Q, s_celsius
BREAKPOINT {
if (s_celsius*1(degC) != celsius) {
s_celsius = celsius
Q = 3^((celsius - 6.3)/10 (degC))
}
ica = vmax*Q*cai/(cai + (.001)*kmp) / 5.18
}