model of DCN pyramidal neuron
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TITLE Gly synapse
COMMENT
MODIFIED to be a faster GLY synapse, taken from GABA synapse
Paul B. Manis - 7 Feb 2000
simple alpha-synapse that generates a single PSP
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reference: McCormick, Wang & Huguenard (1993)
Cerebral Cortex 3(5), 387-398
found in: cat reticular nucleus of thalamus
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Assembled for MyFirstNEURON by Arthur Houweling
ENDCOMMENT
INDEPENDENT {t FROM 0 TO 1 WITH 1 (ms)}
NEURON {
POINT_PROCESS GlySynapse
USEION cl READ ecl VALENCE 1
: negative valence not accepted by nrnivmodl
RANGE onset, gmaxIPSP, e, g, i, w
NONSPECIFIC_CURRENT i
}
UNITS {
(nA) = (nanoamp)
(mV) = (millivolt)
(nS) = (nanomho)
}
PARAMETER {
onset= 25 (ms)
gmaxIPSP= 0 (nS)
w= 1 : weight factor for gmaxIPSP
ecl (mV)
v (mV)
celsius (degC)
}
ASSIGNED {
i (nA)
g (nS)
tadj
}
UNITSOFF
INITIAL {
tadj = 3^((celsius-23.5)/10)
}
BREAKPOINT { LOCAL tt
tt= (t-onset)*tadj
if ((t>onset)&&(tt<740)) {
: the exp() function does not accept arguments smaller than -745
g = w*gmaxIPSP * exp(-tt/15) * (1-exp(-tt/0.5))/0.84
}
else {g = 0}
: -ecl because negative valences can not be specified
i = g * (v-(-ecl))
}
UNITSON